abstract：OBJECTIVE:To determine whether adjusting the intraocular pressure (IOP) change of the trial eye for the IOP change of the fellow eye (i.e., monocular trial) is a better assessment of medication response than testing each eye independently. DESIGN:Analysis of data from a prospective, randomized, clinical trial. PARTIC...

journal_title：Ophthalmology

authors： Bhorade AM,Wilson BS,Gordon MO,Palmberg P,Weinreb RN,Miller E,Chang RT,Kass MA,Ocular Hypertension Treatment Study Group.

更新日期：2010-11-01 00:00:00

abstract：PURPOSE:To present the largest cohort of preschool children screened by the MTI PhotoScreener over a 9-year period from a single, statewide vision screening effort. DESIGN:Cross-sectional study. PARTICIPANTS:We included 147,809 children screened between May 1, 2000, and April 30, 2009 by a photoscreening program. ME...

journal_title：Ophthalmology

authors： Longmuir SQ,Pfeifer W,Leon A,Olson RJ,Short L,Scott WE

更新日期：2010-10-01 00:00:00

abstract：PURPOSE:The aim of the study was to determine whether subconjunctival anesthesia is effective at reducing pain associated with laser retinopexy. DESIGN:This was a single-center, prospective, patient-masked, randomized, controlled trial. PARTICIPANTS:In the primary study group, 65 patients were recruited. Thirty-two p...

journal_title：Ophthalmology

authors： Tesha PE,Giavedoni LR,Berger AR,Altomare F,Chow DR,Navajas EV,Yoganathan P,Wong DT,Principe A

更新日期：2010-09-01 00:00:00

abstract：PURPOSE:To characterize quantitatively the configuration of the anterior ocular segment with ultrasound biomicroscopy (UBM) in a population-based setting. DESIGN:Cross-sectional study. PARTICIPANTS:Ten percent of 4632 residents aged > or =40 years of Kumejima, an island off southwest Japan, were randomly selected. M...

journal_title：Ophthalmology

authors： Henzan IM,Tomidokoro A,Uejo C,Sakai H,Sawaguchi S,Iwase A,Araie M

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVE:To compare pathologic changes in photoreceptors in eyes with resolved central serous chorioretinopathy (CSC) seen on high-resolution images obtained by adaptive optics scanning laser ophthalmoscopy (AO SLO) with visual acuity (VA) and findings on spectral-domain optical coherence tomography (SD OCT). DESIGN:...

journal_title：Ophthalmology

authors： Ooto S,Hangai M,Sakamoto A,Tsujikawa A,Yamashiro K,Ojima Y,Yamada Y,Mukai H,Oshima S,Inoue T,Yoshimura N

更新日期：2010-09-01 00:00:00

abstract：PURPOSE:To evaluate accuracy of intraocular lens (IOL) power calculation formulae (SRK II, SRK/T, Holladay 1, Hoffer Q) in pediatric eyes. DESIGN:Retrospective case series. PARTICIPANTS:One hundred thirty-five eyes of 96 children with congenital, developmental, or acquired cataracts who underwent uncomplicated catara...

journal_title：Ophthalmology

authors： Nihalani BR,VanderVeen DK

更新日期：2010-08-01 00:00:00

abstract：PURPOSE:We sought to determine whether genotype is associated with rate of growth of geographic atrophy (GA) in eyes with age-related macular degeneration (AMD). DESIGN:Prospective analysis of participants in a randomized controlled clinical trial. PARTICIPANTS:We included 114 eyes of 114 participants in the Age-Rela...

journal_title：Ophthalmology

authors： Klein ML,Ferris FL 3rd,Francis PJ,Lindblad AS,Chew EY,Hamon SC,Ott J

更新日期：2010-08-01 00:00:00

abstract：PURPOSE:Autosomal dominant optic atrophy (DOA) is a major cause of visual impairment in young adults that is characterized by selective retinal ganglion cell loss. To define the prevalence and natural history of this optic nerve disorder, we performed a population-based epidemiologic and molecular study of presumed DOA...

journal_title：Ophthalmology

authors： Yu-Wai-Man P,Griffiths PG,Burke A,Sellar PW,Clarke MP,Gnanaraj L,Ah-Kine D,Hudson G,Czermin B,Taylor RW,Horvath R,Chinnery PF

更新日期：2010-08-01 00:00:00

abstract：PURPOSE:To describe macular thickness measured by optical coherence tomography (OCT) in healthy eyes of adult Chinese persons. DESIGN:Population-based cross-sectional study. PARTICIPANTS:Chinese adults aged 30+ years who were residents of Handan, North China. METHODS:The Handan Eye Study is a population-based study ...

journal_title：Ophthalmology

authors： Duan XR,Liang YB,Friedman DS,Sun LP,Wong TY,Tao QS,Bao L,Wang NL,Wang JJ

更新日期：2010-08-01 00:00:00

abstract：PURPOSE:To investigate the frequency of variants in 3 major age-related macular degeneration (AMD)-associated loci in patients of European-American descent with polypoidal choroidal vasculopathy (PCV). DESIGN:Cross-sectional, case-control association study. PARTICIPANTS:Fifty-five patients with PCV, 368 patients with...

journal_title：Ophthalmology

authors： Lima LH,Schubert C,Ferrara DC,Merriam JE,Imamura Y,Freund KB,Spaide RF,Yannuzzi LA,Allikmets R

更新日期：2010-08-01 00:00:00

abstract：PURPOSE:To quantify the vitreous traction created by pneumatic (20-, 23-, and 25-gauge) and electric cutters (20- and 25-gauge) during vitrectomy. DESIGN:Experimental study. PARTICIPANTS:This is a preclinical study, and no patients were involved. METHODS:Five separate cutters for each drive mechanism and gauge (20-,...

journal_title：Ophthalmology

authors： Teixeira A,Chong LP,Matsuoka N,Arana L,Kerns R,Bhadri P,Humayun M

更新日期：2010-07-01 00:00:00

abstract：PURPOSE:To develop a standardized clinical grading system for the management of patients with vernal keratoconjunctivitis (VKC) and to identify the risk factors associated with a worsened outcome of the disease, including decrease of visual acuity and ocular complications development. DESIGN:Retrospective cohort study...

journal_title：Ophthalmology

authors： Sacchetti M,Lambiase A,Mantelli F,Deligianni V,Leonardi A,Bonini S

更新日期：2010-07-01 00:00:00

abstract：PURPOSE:To compare the prevalence of and risk factors for primary open-angle glaucoma (POAG) and primary angle-closure glaucoma (PACG) in urban and rural populations in the Andhra Pradesh Eye Disease Study. DESIGN:A population-based, cross-sectional study using a stratified, random, cluster, and systematic sampling st...

journal_title：Ophthalmology

authors： Garudadri C,Senthil S,Khanna RC,Sannapaneni K,Rao HB

更新日期：2010-07-01 00:00:00

abstract：PURPOSE:To characterize the types and frequencies of image artifacts associated with macular scanning using 2 common spectral-domain optical coherence tomography (SD OCT) instruments and to evaluate the impact of artifacts on foveal thickness measurements. DESIGN:Retrospective, observational chart review. PARTICIPANT...

journal_title：Ophthalmology

authors： Han IC,Jaffe GJ

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:To test whether alternate day vitamin E affects the incidence of age-related macular degeneration (AMD) in a large-scale randomized trial of women. DESIGN:Randomized, double-masked, placebo-controlled trial. PARTICIPANTS:Thirty-nine thousand eight hundred seventy-six apparently healthy female health profess...

journal_title：Ophthalmology

authors： Christen WG,Glynn RJ,Chew EY,Buring JE

更新日期：2010-06-01 00:00:00

abstract：PURPOSE:To determine the refractive predictability, stability, efficacy, and complication rate of femtosecond laser-enabled astigmatic keratotomy for post-keratoplasty astigmatism. DESIGN:A retrospective case series (pilot study). PARTICIPANTS:Thirty-seven eyes of 34 patients. METHODS:All eyes underwent IntraLase-en...

journal_title：Ophthalmology

authors： Kumar NL,Kaiserman I,Shehadeh-Mashor R,Sansanayudh W,Ritenour R,Rootman DS

更新日期：2010-06-01 00:00:00

abstract：PURPOSE:To investigate the frequency of sneezing among patients receiving intravenous sedation and periocular local anesthetic for oculoplastic procedures in a single center. To identify potential risk factors involved. DESIGN:Prospective, consecutive, interventional case series in a single tertiary-referral oculoplas...

journal_title：Ophthalmology

authors： Morley AM,Jazayeri F,Ali S,Malhotra R

更新日期：2010-05-01 00:00:00

abstract：PURPOSE:To study the risk factors, clinical features, and treatment of recurrent fungal keratitis after corneal transplantation. DESIGN:Retrospective, interventional case series. PARTICIPANTS:Eight hundred ninety-nine patients (eyes) with fungal keratitis who underwent corneal transplantation at the Shandong Eye Inst...

journal_title：Ophthalmology

authors： Shi W,Wang T,Xie L,Li S,Gao H,Liu J,Li H

更新日期：2010-05-01 00:00:00

abstract：PURPOSE:Sjögren-Larsson syndrome (SLS), an autosomal recessive hereditary disorder with congenital ichthyosis, spastic diplegia or tetraplegia, and mental retardation, reveals a characteristic macular dystrophy with intraretinal crystals and foveal pseudocysts. Ophthalmic symptoms in SLS are reduced visual acuity and p...

journal_title：Ophthalmology

authors： van der Veen RL,Fuijkschot J,Willemsen MA,Cruysberg JR,Berendschot TT,Theelen T

更新日期：2010-05-01 00:00:00

abstract：PURPOSE:To study the peripheral angiographic features of branch retinal vein occlusions (BRVO) and hemicentral retinal vein occlusions (HRVO) and explore associations with macular edema and neovascularization. DESIGN:Retrospective observational case series. PARTICIPANTS:Seventy-eight outpatients. METHODS:An imaging ...

journal_title：Ophthalmology

authors： Prasad PS,Oliver SC,Coffee RE,Hubschman JP,Schwartz SD

更新日期：2010-04-01 00:00:00

abstract：PURPOSE:To determine the presence of 4 clinically relevant bacterial endosymbionts in Acanthamoeba isolates obtained from patients with Acanthamoeba keratitis (AK) and the possible contribution of endosymbionts to the pathogenesis of AK. DESIGN:Experimental study. PARTICIPANTS:Acanthamoeba isolates (N = 37) recovered...

journal_title：Ophthalmology

authors： Iovieno A,Ledee DR,Miller D,Alfonso EC

更新日期：2010-03-01 00:00:00

abstract：PURPOSE:To assess outcomes 1 year after Descemet's stripping automated endothelial keratoplasty (DSAEK) in comparison with penetrating keratoplasty (PKP) from the Specular Microscopy Ancillary Study (SMAS) of the Cornea Donor Study. DESIGN:Multicenter, prospective, nonrandomized clinical trial. PARTICIPANTS:A total o...

journal_title：Ophthalmology

authors： Price MO,Gorovoy M,Benetz BA,Price FW Jr,Menegay HJ,Debanne SM,Lass JH

更新日期：2010-03-01 00:00:00

abstract：PURPOSE:To evaluate the ability of the GDx Variable Corneal Compensation (VCC) Guided Progression Analysis (GPA) software for detecting glaucomatous progression. DESIGN:Observational cohort study. PARTICIPANTS:The study included 453 eyes from 252 individuals followed for an average of 46+/-14 months as part of the Di...

journal_title：Ophthalmology

authors： Alencar LM,Zangwill LM,Weinreb RN,Bowd C,Vizzeri G,Sample PA,Susanna R Jr,Medeiros FA

更新日期：2010-03-01 00:00:00

abstract：PURPOSE:To determine the clinical efficacy of modified deep lamellar keratoplasty for the treatment of advanced-stage keratoconus with steep curvature. DESIGN:Retrospective, noncomparative clinical trial. PARTICIPANTS:Fifty-nine keratoconus patients with a curvature of more than 60 diopters (D) in 65 eyes were studie...

journal_title：Ophthalmology

authors： Shi W,Li S,Gao H,Wang T,Xie L

更新日期：2010-02-01 00:00:00

abstract：PURPOSE:To identify the prevalence and determinants of self-reported eye care use in Latinos. DESIGN:Population-based ocular epidemiologic study in Latinos aged 40+ years living in La Puente, California. PARTICIPANTS:A total of 5455 participants. METHODS:Univariate, multivariable, and stepwise logistic regression an...

journal_title：Ophthalmology

authors： Morales LS,Varma R,Paz SH,Lai MY,Mazhar K,Andersen RM,Azen SP,Los Angeles Latino Eye Study Group.

更新日期：2010-02-01 00:00:00

abstract：PURPOSE:To characterize reticular pseudodrusen, a potential risk factor for late age-related macular degeneration. DESIGN:Retrospective, observational case series. PARTICIPANTS:Fifty-eight eyes of 33 patients with pseudodrusen (20 female). METHODS:Consecutive patients with reticular pseudodrusen, diagnosed by their ...

journal_title：Ophthalmology

authors： Zweifel SA,Spaide RF,Curcio CA,Malek G,Imamura Y

更新日期：2010-02-01 00:00:00

abstract：PURPOSE:To investigate the relationship between quantitative iris parameters (iris curvature [I-Curv], iris area [I-Area], and iris thickness) and the presence of narrow angles. DESIGN:Cross-sectional, community-based study. PARTICIPANTS:We recruited 2047 subjects >50 years old without ophthalmic symptoms from a comm...

journal_title：Ophthalmology

authors： Wang B,Sakata LM,Friedman DS,Chan YH,He M,Lavanya R,Wong TY,Aung T

更新日期：2010-01-01 00:00:00

abstract：PURPOSE:To determine the efficacy of amblyopia treatment in children identified through a community photoscreening program. DESIGN:Case series. PARTICIPANTS:We included 125 children diagnosed with amblyopia after referral from a photoscreening program. METHODS:Retrospective chart review of 125 amblyopic children ide...

journal_title：Ophthalmology

authors： Teed RG,Bui CM,Morrison DG,Estes RL,Donahue SP

更新日期：2010-01-01 00:00:00

abstract：PURPOSE:To describe Descemet's membrane endothelial keratoplasty (DMEK) techniques, perioperative challenges, management, and visual and refractive outcomes. DESIGN:Prospective, multicenter, consecutive case series. PARTICIPANTS:Sixty eyes of 56 patients with Fuchs' endothelial dystrophy, pseudophakic bullous keratop...

journal_title：Ophthalmology

authors： Price MO,Giebel AW,Fairchild KM,Price FW Jr

更新日期：2009-12-01 00:00:00

abstract：PURPOSE:To evaluate a new high-resolution noncontact biometer (Lenstar; Haag-Streit AG, Koeniz, Switzerland) using optical low-coherence reflectometry and to compare the clinical measurements with those obtained from the IOLMaster (Carl Zeiss, Jena, Germany) and the Pachmumeter (Haag-Streit AG). DESIGN:Exploratory eva...

journal_title：Ophthalmology

authors： Rohrer K,Frueh BE,Wälti R,Clemetson IA,Tappeiner C,Goldblum D

更新日期：2009-11-01 00:00:00

abstract：PURPOSE:To characterize the demographics of patients with dacryolithiasis and to compare patients who have canalicular concretions with patients who have lacrimal sac and duct dacryoliths. DESIGN:Comparative case series study and literature review. PARTICIPANTS:A total of 327 consecutive patients undergoing external ...

journal_title：Ophthalmology

authors： Repp DJ,Burkat CN,Lucarelli MJ

更新日期：2009-11-01 00:00:00

abstract：OBJECTIVE:To determine whether glaucoma patients with progressive optic disc change have subsequent visual field progression earlier and at a faster rate compared with those without disc change. DESIGN:Prospective, longitudinal, cohort study. PARTICIPANTS AND CONTROLS:Eighty-one patients with open-angle glaucoma. ME...

journal_title：Ophthalmology

authors： Chauhan BC,Nicolela MT,Artes PH

更新日期：2009-11-01 00:00:00

abstract：PURPOSE:To apply lessons learned in the treatment of systemic hypertension to the problem of nonadherence in glaucoma medical therapy. CLINICAL RELEVANCE:Although physicians recognize that nonadherence with glaucoma medication is a problem, most lack the skill set to identify nonadherent patients, to identify the caus...

journal_title：Ophthalmology

authors： Budenz DL

更新日期：2009-11-01 00:00:00

abstract：OBJECTIVE:Subconjunctival hemorrhage (SCH) is a relatively common disease, but there have been no reports concerning the relationship between SCH and conjunctivochalasis (CCh). We compared the grade of CCh between patients with SCH and control patients. DESIGN:Prospective, nonrandomized study. PARTICIPANTS:A total of...

journal_title：Ophthalmology

authors： Mimura T,Usui T,Yamagami S,Funatsu H,Noma H,Honda N,Fukuoka S,Shirakawa R,Hotta H,Amano S

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVE:To investigate the genetic causes of complete and incomplete achromatopsia (ACHM) and assess the association between disease-causing mutations, phenotype at diagnosis, and visual prognosis. DESIGN:Clinic-based, longitudinal, multicenter study. PARTICIPANTS:Probands with complete ACHM (n = 35), incomplete AC...

journal_title：Ophthalmology

authors： Thiadens AA,Slingerland NW,Roosing S,van Schooneveld MJ,van Lith-Verhoeven JJ,van Moll-Ramirez N,van den Born LI,Hoyng CB,Cremers FP,Klaver CC

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVE:To determine if glaucoma is associated with driving limitation or cessation. DESIGN:Cross-sectional analysis within a longitudinal, population-based cohort study. PARTICIPANTS AND CONTROLS:One thousand one hundred thirty-five ever-drivers between 73 and 93, including 70 subjects with unilateral and 68 subje...

journal_title：Ophthalmology

authors： Ramulu PY,West SK,Munoz B,Jampel HD,Friedman DS

更新日期：2009-10-01 00:00:00

abstract：PURPOSE:To describe a systematic approach for managing the structural adnexal anomalies encountered in Fraser syndrome, a multisystem, autosomal recessive condition associated with cryptophthalmos. DESIGN:Retrospective, noncomparative, interventional case series. PARTICIPANTS:All patients with Fraser syndrome-related...

journal_title：Ophthalmology

authors： Saleh GM,Hussain B,Verity DH,Collin JR

更新日期：2009-09-01 00:00:00

abstract：OBJECTIVE:To describe the results of revision surgery for complications of trabeculectomy in a case series from an academic glaucoma service. DESIGN:Retrospective case series. PARTICIPANTS:A total of 177 eyes of 167 adult patients who underwent revision of trabeculectomy at the Wilmer Eye Institute between 1994 and 2...

journal_title：Ophthalmology

authors： Radhakrishnan S,Quigley HA,Jampel HD,Friedman DS,Ahmad SI,Congdon NG,McKinnon S

更新日期：2009-09-01 00:00:00

abstract：PURPOSE:To evaluate changes in posterior corneal curvature as a possible cause of the hyperopic refractive shift observed after Descemet's stripping automated endothelial keratoplasty (DSAEK). DESIGN:Prospective, noncomparative, interventional case series. PARTICIPANTS:Thirty-four eyes of 29 patients with Fuchs' endo...

journal_title：Ophthalmology

authors： Scorcia V,Matteoni S,Scorcia GB,Scorcia G,Busin M

更新日期：2009-09-01 00:00:00

abstract：PURPOSE:To evaluate visual outcomes and astigmatism in patients who underwent penetrating keratoplasty (PK) with 2 different incision techniques. DESIGN:Retrospective comparison of a consecutive surgical series. PARTICIPANTS:Fifty-seven consecutive patients who underwent PK at the University of California, Irvine, ac...

journal_title：Ophthalmology

authors： Farid M,Steinert RF,Gaster RN,Chamberlain W,Lin A

更新日期：2009-09-01 00:00:00